Study on risk factors of cardiovascular disease and the status of bone mineral density in women with hypoestrogenism

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Zhonghua fu chan ke za zhi

Zhonghua Fu Chan Ke Za Zhi

Oct

734

739

JID: 16210370R; 0 (Estrogens); 0 (Lipids); ppublish

China

0529-567X; 0529-567X

PMID: 24406128

chi

English Abstract; Journal Article; IM

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24406128

OBJECTIVE: To study risk factors of cardiovascular disease (CVD) and status of bone mineral density (BMD) in women with hypoestrogenism. METHODS: From Jul 2011 to April 2013, a total of 256 women with hypoestrogenism in the First Affiliated Hospital of Shanxi Medical University were enrolled in this retrospective study, which were divided into four groups:133 women in ppausal group, 25 women in premature ovarian failure (POF) group, 67 women in menopausal transition group and 31 women in premature ovarian failure transition group.General statue, CVD risk factors and BMD were compared among four groups.General statue include menopausal period, menopausal symptoms (Kupperman Index), CVD risk factors include body mass index, blood pressure, waist circumference, waist-hip ratio, blood lipids and glucose, BMD include left hip, lumbar spine bone mineral density and T or Z value. RESULTS: (1) The median menopausal period were 3.4 years in postmenopausal group and 3.6 years in premature ovarian failure group, which did not show no statistical difference (P > 0.05).Kupperman Index in four groups were 12 in postmenopausal group, 9 in POF group, 9 in menopausal transition group and 8 in premature ovarian failure transition group, which reached statistical difference (P 0.05); the systolic blood pressure in four groups were 120, 110, 110, 110 mm Hg (1 mm Hg = 0.133 kPa), their differences were statistically significance (P 0.05); the systolic blood pressure in four groups were 120, 110, 110, 110 mm Hg (1 mm Hg = 0.133 kPa), their differences were statistically significance (P 0.05).(3) The abnormal rate of lower bone mass in lumbar spine were 57% (46/81) postmenopausal group, 8/15 in POF group, 32% (9/28) in menopausal transition group, 12/19 in premature ovarian failure transition group, and osteoporosis was 9% (7/81), 3/15, 1% (3/28) and 0 respectively , their differences were statistically different (P

Zhao,F., Guo,X.T., Cheng,Y., Yang,Z.F., Liu,H.P.

Department of Gynaecology and Obstetrics, First Hospital of Shanxi Medical University, Taiyuan 030001, China.; Department of Gynaecology and Obstetrics, First Hospital of Shanxi Medical University, Taiyuan 030001, China. Email: gxt_ 999@163.com.; Departme

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2013