Smoke constituent exposure and smoking topography of adolescent daily cigarette smokers

Journal Article

Print(0)

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco

Nicotine Tob.Res.

Oct

853

862

LR: 20151119; GR: 1 F31 NR07460/NR/NINR NIH HHS/United States; GR: M01RR00034/RR/NCRR NIH HHS/United States; JID: 9815751; 0 (Ganglionic Stimulants); 6M3C89ZY6R (Nicotine); 7U1EE4V452 (Carbon Monoxide); K5161X06LL (Cotinine); ppublish

England

1462-2203; 1462-2203

PMID: 15700921

eng

Journal Article; Research Support, U.S. Gov't, P.H.S.; IM

Unknown(0)

15700921

Adolescent smoking prevalence is a major health concern, with 24.4% reporting smoking in the past 30 days and 15.8% considered daily smokers. The purpose of this study was to characterize biobehavioral nicotine dependence, smoke constituent exposure and smoking topography in adolescent daily smokers. Relationships among biological markers of nicotine dependence (nicotine boost, carbon monoxide [CO] boost and cotinine levels) with existing self-report measures (modified Fagerstrom Tolerance Questionnaire [mFTQ] and the motivations for smoking scale) were examined. Gender differences were characterized. Fifty adolescents 13-18 years old were recruited for the study, 50% female. CO, plasma nicotine levels pre- and postcigarette, cotinine, and smoking topography were measured during a smoking bout with participant's usual cigarette. Average CO boost, pre- to postcigarette was 7.2 + 3.6 ppm, baseline cotinine level averaged 224.0 +/- 169.6 ng/ml and nicotine boost averaged 23.4 +/- 21.7 ng/ml. Mean puffs per cigarette was 14.2 +/- 6.3. Males had significantly higher total puff volumes, but similar smoke constituent exposure to females, and higher handling of cigarettes as smoking motive. In regression analysis, 35% of variance in tobacco use, as indicated by baseline cotinine concentration, was explained by maximum puff duration, postcigarette CO level, and nicotine dependence, as measured by the mFTQ. Results indicated adolescents had considerable smoke constituent exposure and nicotine dependence suggesting the importance of appropriate smoking cessation treatment.

Adolescent, Adolescent Behavior, Carbon Monoxide/analysis, Cotinine/analysis, Cross-Sectional Studies, Female, Ganglionic Stimulants/pharmacology, Humans, Male, Nicotine/pharmacology, Sex Factors, Smoking/psychology, Smoking Cessation, Tobacco Use Disorder/physiopathology/psychology

Wood,T., Wewers,M. E., Groner,J., Ahijevych,K.

Capital University School of Nursing, Columbus, Ohio, USA.

http://vp9py7xf3h.search.serialssolutions.com/?charset=utf-8&pmid=15700921

2004