Journal Article
Print(0)
Journal of general internal medicine
J.Gen.Intern.Med.
Sep
25
9
969
976
LR: 20151119; GR: R01 CA091912/CA/NCI NIH HHS/United States; GR: R01 CA091912/CA/NCI NIH HHS/United States; JID: 8605834; 0 (Chewing Gum); 0 (Nicotinic Agonists); 0 (Placebos); 6M3C89ZY6R (Nicotine); OID: NLM: PMC2917663; 2009/06/23 [received]; 2010/04/07
United States
1525-1497; 0884-8734
PMID: 20495885
eng
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; IM
10.1007/s11606-010-1386-x [doi]
Unknown(0)
20495885
BACKGROUND: A high proportion of African-American smokers are light smokers, and they experience low smoking cessation rates and disproportionately high tobacco-related morbidity; yet no studies have examined tobacco treatment adherence in this group. OBJECTIVES: To determine the predictors of adherence to nicotine gum and counseling among African-American light smokers (defined as smoking < or =10 cigarettes/day), and the effects of adherence on smoking cessation. DESIGN: Data were from a 2 x 2 randomized, placebo-controlled smoking cessation trial of nicotine gum (2 mg versus placebo) and counseling (motivational interviewing versus health education). PARTICIPANTS: Seven hundred fifty-five African-American light smokers at a community-based clinic. MEASUREMENTS: Demographic and health-related information, smoking behaviors, psychosocial variables, adherence to nicotine gum and counseling, and cotinine-verified 7-day abstinence from smoking at week-26 follow-up. RESULTS: A logistic regression model showed that having a higher body mass index (OR = 1.03, 95% CI = 1.01 to 1.05), more quit attempts in the past year (OR = 1.04, 95% CI = 1.01 to 1.07), higher baseline exhaled carbon monoxide (OR = 1.22, 95% CI = 1.01 to 1.48), and higher perceived stress (OR = 1.12, 95% CI = 1.03 to 1.22) increased the likelihood of adherence to nicotine gum. Being a high school graduate was a predictor of adherence to counseling (OR = 1.58, 95% CI = 1.02 to 2.44). Surprisingly, being adherent to nicotine gum significantly reduced the odds of smoking cessation (OR = 0.50, CI = 0.28 to 0.87). On the other hand, adherence to counseling dramatically increased the likelihood of smoking cessation (OR = 3.32, CI = 1.36 to 8.08). CONCLUSIONS: Individual risk factors may influence adherence to nicotine gum and counseling. Improving psychological interventions and promoting adherence to counseling may increase overall smoking cessation success among African-American light smokers.
Adult, African Americans, Behavior Therapy, Body Mass Index, Chewing Gum, Double-Blind Method, Female, Humans, Male, Medication Adherence/ethnology, Middle Aged, Nicotine/therapeutic use, Nicotinic Agonists/therapeutic use, Odds Ratio, Placebos, Smoking/ethnology/prevention & control, Smoking Cessation/ethnology/methods/psychology, Treatment Failure
Okuyemi,K. S., Zheng,H., Guo,H., Ahluwalia,J. S.
Program in Health Disparities Research, University of Minnesota Medical School, Minneapolis, MN, USA. kokuyemi@umn.edu
20100521
PMC2917663
http://vp9py7xf3h.search.serialssolutions.com/?charset=utf-8&pmid=20495885
2010