Journal Article

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Acta crystallographica.Section E, Structure reports online

Acta Crystallogr.Sect.E.Struct.Rep.Online

1-Oct

68

Pt 10

o2932

JID: 101089178; OID: NLM: PMC3470306; 2012/07/09 [received]; 2012/09/07 [accepted]; 2012/09/15 [epublish]; ppublish

United States

1600-5368; 1600-5368

PMID: 23125719

eng

Journal Article

10.1107/S160053681203841X [doi]

Unknown(0)

23125719

In the title mol-ecular salt (systematic name: 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]eth-yl}-9-hy-droxy-2-methyl- 1,6,7,8,9,9a-hexa-hydro-pyrido[1,2-a]pyrimidin-4-one nitrate), C(23)H(29)FN(4)O(3) (+).NO(3) (-), the piperidine ring displays a chair conformation and its N atom is protonated; the N-H bond is in an axial orientation. The ring bearing the hy-droxy group exhibits a half-chair conformation. The hy-droxy group as well as the adjacent methyl-ene group are disordered over two sets of sites in a 0.823 (5):0.177 (5) ratio. In the crystal, O-Hcdots, three dots, centeredN, O-Hcdots, three dots, centeredO, N-Hcdots, three dots, centeredO and N-Hcdots, three dots, centeredN hydrogen bonds connect the components into a three-dimensional network.

Ge,J., Luo,Y.H.

School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.

20120915

PMC3470306

http://vp9py7xf3h.search.serialssolutions.com/?charset=utf-8&pmid=23125719

2012