The effects of non-surgical periodontal therapy on oxidant and anti-oxidant status in smokers with chronic periodontitis

Journal Article

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Archives of Oral Biology

Arch.Oral Biol.

Jun

717

723

LR: 20151119; CI: Copyright (c) 2012; JID: 0116711; 0 (Antioxidants); 0 (Benzothiazoles); 0 (Fluorescent Dyes); 0 (Indicators and Reagents); 0 (Oxidants); 0 (Phenols); 0 (Sulfonic Acids); 0 (Sulfoxides); 28752-68-3 (2,2'-azino-di-(3-ethylbenzothiazoline)-

England

1879-1506; 0003-9969

PMID: 23261252

eng

Journal Article; Research Support, Non-U.S. Gov't; D; IM

10.1016/j.archoralbio.2012.11.009 [doi]

Unknown(0)

23261252

AIM: The aim of this study was to determine the effect of non-surgical periodontal treatment on gingival crevicular fluid (GCF) and serum oxidant-antioxidant levels in smoking and non-smoking patients with chronic periodontitis. METHODS: Twenty-nine patients with chronic periodontitis (15 smokers (CP-S) and 14 non-smokers (CP-NS)) and 20 periodontally healthy subjects (10 smokers (H-S) and 10 non-smokers (H-NS)) totalling 49 subjects were included in this study. GCF was collected from at least two pre-selected sites (one moderate and one deep pocket) in patients with CP. In the healthy group, GCF samples were collected from one site. Probing pocket depth, clinical attachment level (CAL), gingival and plaque indices, and bleeding on probing were measured. To determine serum total oxidant status (TOS) and total antioxidant status (TAS), venous blood was drawn from each subject. The GCF, serum sampling, and clinical measurements were recorded at baseline and 6 weeks after periodontal treatment. RESULTS: The study showed statistically significant improvement of clinical parameters after periodontal treatment in both smokers and non-smokers. In the CP-S group, there were no significant differences in GCF TAS levels at both moderate and deep pocket sites between baseline and 6 weeks (p>0.05). GCF TAS levels in the CP-NS groups were significantly increased (p0.05). Serum TOS levels in the CP-S and CP-NS groups were significantly decreased (p

Elsevier Ltd

Akpinar,A., Toker,H., Ozdemir,H., Bostanci,V., Aydin,H.

Department of Periodontology, Cumhuriyet University Faculty of Dentistry, Sivas, Turkey. aysun@cumhuriyet.edu.tr

20121220

http://vp9py7xf3h.search.serialssolutions.com/?charset=utf-8&pmid=23261252

2013