Journal Article

Print(0)

Inhalation toxicology

Inhal.Toxicol.

Oct

24

12

850

857

LR: 20151119; JID: 8910739; 0 (Air Pollutants); 0 (Aldehydes); 0 (Glycols); 0 (Nitrosamines); 0 (Particulate Matter); 0 (Polycyclic Hydrocarbons, Aromatic); 0 (Tobacco Smoke Pollution); 0 (Volatile Organic Compounds); 6M3C89ZY6R (Nicotine); ppublish

England

1091-7691; 0895-8378

PMID: 23033998

eng

Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; IM

10.3109/08958378.2012.724728 [doi]

Unknown(0)

23033998

CONTEXT: Electronic cigarettes (e-cigarettes) have earned considerable attention recently as an alternative to smoking tobacco, but uncertainties about their impact on health and indoor air quality have resulted in proposals for bans on indoor e-cigarette use. OBJECTIVE: To assess potential health impacts relating to the use of e-cigarettes, a series of studies were conducted using e-cigarettes and standard tobacco cigarettes. METHODS AND MATERIALS: Four different high nicotine e-liquids were vaporized in two sets of experiments by generic 2-piece e-cigarettes to collect emissions and assess indoor air concentrations of common tobacco smoke by products. Tobacco cigarette smoke tests were conducted for comparison. RESULTS: Comparisons of pollutant concentrations were made between e-cigarette vapor and tobacco smoke samples. Pollutants included VOCs, carbonyls, PAHs, nicotine, TSNAs, and glycols. From these results, risk analyses were conducted based on dilution into a 40 m(3) room and standard toxicological data. Non-cancer risk analysis revealed "No Significant Risk" of harm to human health for vapor samples from e-liquids (A-D). In contrast, for tobacco smoke most findings markedly exceeded risk limits indicating a condition of "Significant Risk" of harm to human health. With regard to cancer risk analysis, no vapor sample from e-liquids A-D exceeded the risk limit for either children or adults. The tobacco smoke sample approached the risk limits for adult exposure. CONCLUSIONS: For all byproducts measured, electronic cigarettes produce very small exposures relative to tobacco cigarettes. The study indicates no apparent risk to human health from e-cigarette emissions based on the compounds analyzed.

McAuley,T.R., Hopke,P.K., Zhao,J., Babaian,S.

Consulting for Health, Air, Nature, & A Greener Environment, LLC (CHANGE), Corporate Headquarters, Queensbury, NY 12804-9358, USA. mcauleyt@airqualitychange.com

http://vp9py7xf3h.search.serialssolutions.com/?charset=utf-8&pmid=23033998

2012